ISSN 1662-4009 (online)

ey0020.7-12 | Adrenal Function and Cancer Treatment | ESPEYB20

7.12. The assessment of the hypothalamic-pituitary-adrenal axis after oncological treatment in pediatric patients with acute lymphoblastic leukemia

B Hull , A Wędrychowicz , M Ossowska , A Furtak , J Badacz , S Skoczeń , JB Starzyk

Brief summary: Chemotherapy, radiotherapy and corticosteroids used to treat acute lymphoblastic leukemia (ALL) can have endocrine side-effects, such as adrenal insufficiency (AI). This cross-sectional single-centre study aimed to assess AI frequency after completion of ALL therapy, by comparison to healthy controls matched for age and sex, and to identify biomarkers of adrenal function and reserve.Study patients were at least 16 months post-completion of...